Definition: Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.

Summary:
Note that enzymes of class EC:1.6.99.- should also be annotated to this term.

Parent Classes:
GO:0016491 - oxidoreductase activity

Child Classes:
GO:0003954 - NADH dehydrogenase activity (27) ,
GO:0016652 - oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor (4) ,
GO:0016653 - oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor (1) ,
GO:0016655 - oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (32) ,
GO:0016657 - oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor (4) ,
GO:0016668 - oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor (10)

Term Members:
hydrogenase 4, small subunit ,
member of SoxR-reducing complex ,
hydrogenase 4, large subunit ,
NADH:ubiquinone oxidoreductase, chain G ,
NADH:ubiquinone oxidoreductase, chain F ,
hydrogenase 3 and formate hydrogenlyase complex, HycG subunit ,
hydrogenase 3, large subunit ,
NADH:ubiquinone oxidoreductase, chain I ,
hydrogenase 4, component E ,
large subunit of periplasmic nitrate reductase, molybdoprotein ,
nitrate reductase Z, α subunit ,
nitrate reductase A, α subunit

Unification Links: GO:0016651

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